Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal   Applicators for the Management of Preinvasive Cervical Lesions

Coravu, Violeta; Turcan, Natalia; Mergeanu, Mara; Sajin, Maria; Zugravu, Corina Aurelia; Cirstoiu, Monica Mihaela

Violeta Coravu, Natalia Turcan, Mara Mergeanu, Maria Sajin, Corina Aurelia Zugravu, Monica Mihaela Cirstoiu

Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions

Abstract:

A successfully implemented screening program for cervical cancer is essential for detecting cervical intraepithelial lesions which offer the possibility of appropriate management and monitoring, implicitly the limitation of the progression to an invasive form of cancer. For different grades of squamous intraepithelial lesions, the use of vaginal tablets or applicators based on various natural substances as hyaluronic acid, beta-glucan and Coriolus Versicolor is possible with the purpose of expectative management or prior and post excisional intervention. We present the incidence trend of abnormal Pap smear results for the last five years in the University Emergency Hospital of Bucharest, with a summary of the literature regarding the biochemical mechanism of the main natural components from vaginal tablets used in the management of precancerous cervical lesions HPV induced and we share our personal experience with three clinical cases that benefited from this therapy. As there is a therapeutic window between the Pap-smear result, colposcopy and preparing for intervention, local treatment with natural components is a suitable choice as it is easy to use, inexpensive and efficient. The conclusion we reached is that the vaginal treatment with natural substances can be useful in terms of improving the local inflammatory process on the one hand and lubricating and regenerating tissues with the improvement of subsequent procedural performance on the other.

Keywords:
precancerous cervical lesions; hyaluronic acid; beta-glucan; Coriolus Versicolor

Issue: 2021, Volume 72, Issue 4

Pages: 175-182

Publication date: 2021/10/29

https://doi.org/10.37358/RC.21.4.8466

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
CORAVU, V., TURCAN, N., MERGEANU, M., SAJIN, M., ZUGRAVU, C.A., CIRSTOIU, M.M., Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions, Rev. Chim., 72(4), 2021, 175-182.

Vancouver
Coravu V, Turcan N, Mergeanu M, Sajin M, Zugravu CA, Cirstoiu MM. Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions. Rev. Chim.[internet]. 2021 Apr;72(4):175-182. Available from: https://doi.org/10.37358/RC.21.4.8466

APA 6th edition
Coravu, V., Turcan, N., Mergeanu, M., Sajin, M., Zugravu, C.A. & Cirstoiu, M.M. (2021). Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions. Revista de Chimie, 72(4), 175-182. https://doi.org/10.37358/RC.21.4.8466

Harvard
Coravu, V., Turcan, N., Mergeanu, M., Sajin, M., Zugravu, C.A., Cirstoiu, M.M. (2021). 'Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions', Revista de Chimie, 72(4), pp. 175-182. https://doi.org/10.37358/RC.21.4.8466

IEEE
V. Coravu, N. Turcan, M. Mergeanu, M. Sajin, C.A. Zugravu, M.M. Cirstoiu, "Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions". Revista de Chimie, vol. 72, no. 4, pp. 175-182, 2021. [online]. https://doi.org/10.37358/RC.21.4.8466

Text
Violeta Coravu, Natalia Turcan, Mara Mergeanu, Maria Sajin, Corina Aurelia Zugravu, Monica Mihaela Cirstoiu,
Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions,
Revista de Chimie,
Volume 72, Issue 4,
2021,
Pages 175-182,
ISSN 2668-8212,
https://doi.org/10.37358/RC.21.4.8466.
(https://revistadechimie.ro/Articles.asp?ID=8466)
Keywords: precancerous cervical lesions; hyaluronic acid; beta-glucan; Coriolus Versicolor

RIS
TY - JOUR
T1 - Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions
A1 - Coravu, Violeta
A2 - Turcan, Natalia
A3 - Mergeanu, Mara
A4 - Sajin, Maria
A5 - Zugravu, Corina Aurelia
A6 - Cirstoiu, Monica Mihaela
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2021
VL - 72
IS - 4
SP - 175
EP - 182
UR - https://doi.org/10.37358/RC.21.4.8466
KW - precancerous cervical lesions
KW - hyaluronic acid
KW - beta-glucan
KW - Coriolus Versicolor
ER -

BibTex
@article{RevCh2021P175,
author = {Coravu Violeta and Turcan Natalia and Mergeanu Mara and Sajin Maria and Zugravu Corina Aurelia and Cirstoiu Monica Mihaela},
title = {Biochemical Mechanisms of Action of Natural Ingredients from the Vaginal Applicators for the Management of Preinvasive Cervical Lesions},
journal = {Revista de Chimie},
volume = {72},
number = {4},
pages = {175-182},
year = {2021},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.21.4.8466},
url = {https://revistadechimie.ro/Articles.asp?ID=8466}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)