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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2020, Volume 71, Issue 3, 516-521

https://doi.org/10.37358/RC.20.3.8026

Georgiana Bianca Constantin, Sorin Berbece, Dragos Voicu, Luiza Nechita, Corina Palivan Manole, Alexandra Toma, Raul Mihailov, Oana Mihailov, Bogdan Stefanescu, Ciprian Dinu

The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency

Abstract:

Clostridium difficile infection has increased over the past decades. Surgical patients, especially those undergoing intestinal surgery, have higher rates of this infection. Patients infected with Clostridium difficile are more likely to have postoperative complications and higher rates of mortality. We will present the results of a retrospective study made in the 2nd clinic of Surgery at the Clinical Emergency County Hospital “Sf. Ap. Andrei” Galati. This study includes 431 patients with complicated colorectal cancers operated in emergency between 2007 and 2016. All the patients infected with Clostridium difficile received oral Metronidazole. Only one of the infected patients presented a recurrence which was treated with oral vancomycin. The treatment of Clostridium difficile infection has become a global public health challenge. Colorectal surgery is a documented risk factor for Clostridium difficile infection. The prevalence of Clostridium difficile infection has grown in the last years and this increase has been particularly apparent among surgical patients. In a large intestine weakened by cancer, the risk of this infection can increase even more. New strategies to prevent the Clostridium difficile infection are required.
Keywords:
colorectal cancer; complications; Clostridium difficile infection; impact; treatment

Issue: 2020, Volume 71, Issue 3
Pages: 516-521
Publication date: 2020/4/3
https://doi.org/10.37358/RC.20.3.8026
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
CONSTANTIN, G.B., BERBECE, S., VOICU, D., NECHITA, L., MANOLE, C.P., TOMA, A., MIHAILOV, R., MIHAILOV, O., STEFANESCU, B., DINU, C., The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency, Rev. Chim., 71(3), 2020, 516-521.

Vancouver
Constantin GB, Berbece S, Voicu D, Nechita L, Manole CP, Toma A, Mihailov R, Mihailov O, Stefanescu B, Dinu C. The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency. Rev. Chim.[internet]. 2020 Mar;71(3):516-521. Available from: https://doi.org/10.37358/RC.20.3.8026


APA 6th edition
Constantin, G.B., Berbece, S., Voicu, D., Nechita, L., Manole, C.P., Toma, A.,... Dinu, C. (2020). The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency. Revista de Chimie, 71(3), 516-521. https://doi.org/10.37358/RC.20.3.8026


Harvard
Constantin, G.B., Berbece, S., Voicu, D., Nechita, L., Manole, C.P., Toma, A., Mihailov, R., Mihailov, O., Stefanescu, B., Dinu, C. (2020). 'The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency', Revista de Chimie, 71(3), pp. 516-521. https://doi.org/10.37358/RC.20.3.8026


IEEE
G.B. Constantin, S. Berbece, D. Voicu, L. Nechita, C.P. Manole, A. Toma, R. Mihailov, O. Mihailov, B. Stefanescu, C. Dinu, "The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency". Revista de Chimie, vol. 71, no. 3, pp. 516-521, 2020. [online]. https://doi.org/10.37358/RC.20.3.8026


Text
Georgiana Bianca Constantin, Sorin Berbece, Dragos Voicu, Luiza Nechita, Corina Palivan Manole, Alexandra Toma, Raul Mihailov, Oana Mihailov, Bogdan Stefanescu, Ciprian Dinu,
The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency,
Revista de Chimie,
Volume 71, Issue 3,
2020,
Pages 516-521,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.3.8026.
(https://revistadechimie.ro/Articles.asp?ID=8026)
Keywords: colorectal cancer; complications; Clostridium difficile infection; impact; treatment


RIS
TY - JOUR
T1 - The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency
A1 - Constantin, Georgiana Bianca
A2 - Berbece, Sorin
A3 - Voicu, Dragos
A4 - Nechita, Luiza
A5 - Manole, Corina Palivan
A6 - Toma, Alexandra
A7 - Mihailov, Raul
A8 - Mihailov, Oana
A9 - Stefanescu, Bogdan
A10 - Dinu, Ciprian
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 3
SP - 516
EP - 521
UR - https://doi.org/10.37358/RC.20.3.8026
KW - colorectal cancer
KW - complications
KW - Clostridium difficile infection
KW - impact
KW - treatment
ER -


BibTex
@article{RevCh2020P516,
author = {Constantin Georgiana Bianca and Berbece Sorin and Voicu Dragos and Nechita Luiza and Manole Corina Palivan and Toma Alexandra and Mihailov Raul and Mihailov Oana and Stefanescu Bogdan and Dinu Ciprian},
title = {The use of Metronidazole in Clostridium Difficile Infection at Patients with Colorectal Cancers operated in Emergency},
journal = {Revista de Chimie},
volume = {71},
number = {3},
pages = {516-521},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.3.8026},
url = {https://revistadechimie.ro/Articles.asp?ID=8026}
}
 
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