Challenges of Valproate Treatment During Pregnancy: Pros and Cons

Arbune, Anca-Adriana; Craiu, Dana; Cuciureanu, Iulian Dan; Iulian, Constantin; Pavel, Liliana Lacramioara; Berbece, Ion Sorin; Grigore, Camelia Ana; Dulamea, Adriana

Anca-Adriana Arbune, Dana Craiu, Iulian Dan Cuciureanu, Constantin Iulian, Liliana Lacramioara Pavel, Ion Sorin Berbece, Camelia Ana Grigore, Adriana Dulamea

Challenges of Valproate Treatment During Pregnancy: Pros and Cons

Abstract:

Valproic acid and its salt, sodium valproate, are an effective treatment for epilepsy, the most common chronic neurologic disorder worldwide. Teratogenic associations reported after embryofetal exposure has limited the recommendations of valproate use in women of childbearing age, after careful evaluation of the benefits and risks of this medication. The mechanisms of valproate damage during pregnancy are complex and incompletely clarified up to date. Maternal and fetal impact of valproate is a critical issue, standing at the base of the new consensus on practical guidelines for clinical use of antiepileptic treatment in fertile women.

Keywords:
pregnancy; epilepsy; Valproate

Issue: 2020, Volume 71, Issue 2

Pages: 456-459

Publication date: 2020/3/3

https://doi.org/10.37358/RC.20.2.7949

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ARBUNE, A., CRAIU, D., CUCIUREANU, I.D., IULIAN, C., PAVEL, L.L., BERBECE, I.S., GRIGORE, C.A., DULAMEA, A., Challenges of Valproate Treatment During Pregnancy: Pros and Cons, Rev. Chim., 71(2), 2020, 456-459.

Vancouver
Arbune A, Craiu D, Cuciureanu ID, Iulian C, Pavel LL, Berbece IS, Grigore CA, Dulamea A. Challenges of Valproate Treatment During Pregnancy: Pros and Cons. Rev. Chim.[internet]. 2020 Feb;71(2):456-459. Available from: https://doi.org/10.37358/RC.20.2.7949

APA 6th edition
Arbune, A., Craiu, D., Cuciureanu, I.D., Iulian, C., Pavel, L.L., Berbece, I.S., Grigore, C.A. & Dulamea, A. (2020). Challenges of Valproate Treatment During Pregnancy: Pros and Cons. Revista de Chimie, 71(2), 456-459. https://doi.org/10.37358/RC.20.2.7949

Harvard
Arbune, A., Craiu, D., Cuciureanu, I.D., Iulian, C., Pavel, L.L., Berbece, I.S., Grigore, C.A., Dulamea, A. (2020). 'Challenges of Valproate Treatment During Pregnancy: Pros and Cons', Revista de Chimie, 71(2), pp. 456-459. https://doi.org/10.37358/RC.20.2.7949

IEEE
A. Arbune, D. Craiu, I.D. Cuciureanu, C. Iulian, L.L. Pavel, I.S. Berbece, C.A. Grigore, A. Dulamea, "Challenges of Valproate Treatment During Pregnancy: Pros and Cons". Revista de Chimie, vol. 71, no. 2, pp. 456-459, 2020. [online]. https://doi.org/10.37358/RC.20.2.7949

Text
Anca-Adriana Arbune, Dana Craiu, Iulian Dan Cuciureanu, Constantin Iulian, Liliana Lacramioara Pavel, Ion Sorin Berbece, Camelia Ana Grigore, Adriana Dulamea,
Challenges of Valproate Treatment During Pregnancy: Pros and Cons,
Revista de Chimie,
Volume 71, Issue 2,
2020,
Pages 456-459,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.2.7949.
(https://revistadechimie.ro/Articles.asp?ID=7949)
Keywords: pregnancy; epilepsy; Valproate

RIS
TY - JOUR
T1 - Challenges of Valproate Treatment During Pregnancy: Pros and Cons
A1 - Arbune, Anca-Adriana
A2 - Craiu, Dana
A3 - Cuciureanu, Iulian Dan
A4 - Iulian, Constantin
A5 - Pavel, Liliana Lacramioara
A6 - Berbece, Ion Sorin
A7 - Grigore, Camelia Ana
A8 - Dulamea, Adriana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 2
SP - 456
EP - 459
UR - https://doi.org/10.37358/RC.20.2.7949
KW - pregnancy
KW - epilepsy
KW - Valproate
ER -

BibTex
@article{RevCh2020P456,
author = {Arbune Anca-Adriana and Craiu Dana and Cuciureanu Iulian Dan and Iulian Constantin and Pavel Liliana Lacramioara and Berbece Ion Sorin and Grigore Camelia Ana and Dulamea Adriana},
title = {Challenges of Valproate Treatment During Pregnancy: Pros and Cons},
journal = {Revista de Chimie},
volume = {71},
number = {2},
pages = {456-459},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.2.7949},
url = {https://revistadechimie.ro/Articles.asp?ID=7949}
}

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