Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation

Gorea, Maria; Naghiu, Marieta-Adriana; Avram, Alexandra; Petean, Ioan; Mocanu, Aurora; Tomoaia-Cotisel, Maria

Maria Gorea, Marieta-Adriana Naghiu, Alexandra Avram, Ioan Petean, Aurora Mocanu, Maria Tomoaia-Cotisel

Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation

Abstract:

This study is aimed to evaluate the biocompatibility and bioactivity of some new porous forsterite ceramics (FCs) produced from high-purity nano forsterite powder, synthesized by an original sol-gel method, which was subjected to pressing into pellets, by using a poly vinyl alcohol solution as a binding component. Then, the raw pellets were sintered at 1200 °C, 1300 °C, 1400 °C and 1450 °C. The obtained four forsterite ceramics, FC-1200, FC-1300, FC-1400 and FC-1450, were fully characterized by density, porosity and shrinkage measurements. The forsterite ceramics exhibited excellent biocompatibility determined by an in vitro cell viability assay, such as MTT test. Furthermore, the in vitro bioactivity test was performed by immersing the forsterite ceramics into simulated body fluid (SBF) and examining the hydroxyapatite (HAP) formation on forsterite ceramics, as evidenced by XRD, FTIR, SEM with EDX. Moreover, the relationship between porous structure and bioactivity of forsterite ceramics in SBF as well as the performance of FC in a cell culture was evaluated. The findings strongly recommend these forsterite ceramics for biomedical applications, as potential bone substitutes.

Keywords:
forsterite ceramics; cell viability; bioactivity in SBF; hydroxyapatite formation

Issue: 2020, Volume 71, Issue 2

Pages: 343-351

Publication date: 2020/3/3

https://doi.org/10.37358/RC.20.2.7935

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GOREA, M., NAGHIU, M., AVRAM, A., PETEAN, I., MOCANU, A., TOMOAIA-COTISEL, M., Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation, Rev. Chim., 71(2), 2020, 343-351.

Vancouver
Gorea M, Naghiu M, Avram A, Petean I, Mocanu A, Tomoaia-Cotisel M. Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation. Rev. Chim.[internet]. 2020 Feb;71(2):343-351. Available from: https://doi.org/10.37358/RC.20.2.7935

APA 6th edition
Gorea, M., Naghiu, M., Avram, A., Petean, I., Mocanu, A. & Tomoaia-Cotisel, M. (2020). Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation. Revista de Chimie, 71(2), 343-351. https://doi.org/10.37358/RC.20.2.7935

Harvard
Gorea, M., Naghiu, M., Avram, A., Petean, I., Mocanu, A., Tomoaia-Cotisel, M. (2020). 'Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation', Revista de Chimie, 71(2), pp. 343-351. https://doi.org/10.37358/RC.20.2.7935

IEEE
M. Gorea, M. Naghiu, A. Avram, I. Petean, A. Mocanu, M. Tomoaia-Cotisel, "Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation". Revista de Chimie, vol. 71, no. 2, pp. 343-351, 2020. [online]. https://doi.org/10.37358/RC.20.2.7935

Text
Maria Gorea, Marieta-Adriana Naghiu, Alexandra Avram, Ioan Petean, Aurora Mocanu, Maria Tomoaia-Cotisel,
Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation,
Revista de Chimie,
Volume 71, Issue 2,
2020,
Pages 343-351,
ISSN 2668-8212,
https://doi.org/10.37358/RC.20.2.7935.
(https://revistadechimie.ro/Articles.asp?ID=7935)
Keywords: forsterite ceramics; cell viability; bioactivity in SBF; hydroxyapatite formation

RIS
TY - JOUR
T1 - Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation
A1 - Gorea, Maria
A2 - Naghiu, Marieta-Adriana
A3 - Avram, Alexandra
A4 - Petean, Ioan
A5 - Mocanu, Aurora
A6 - Tomoaia-Cotisel, Maria
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2020
VL - 71
IS - 2
SP - 343
EP - 351
UR - https://doi.org/10.37358/RC.20.2.7935
KW - forsterite ceramics
KW - cell viability
KW - bioactivity in SBF
KW - hydroxyapatite formation
ER -

BibTex
@article{RevCh2020P343,
author = {Gorea Maria and Naghiu Marieta-Adriana and Avram Alexandra and Petean Ioan and Mocanu Aurora and Tomoaia-Cotisel Maria},
title = {Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation},
journal = {Revista de Chimie},
volume = {71},
number = {2},
pages = {343-351},
year = {2020},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.20.2.7935},
url = {https://revistadechimie.ro/Articles.asp?ID=7935}
}

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