Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation

Lesan, Andrei; Man, Milena Adina; Nemes, Roxana Maria; Harsovescu, Tudor; Tudorache, Ioan Sorin; Boca, Beatrice Mahler; Pop, Carmen Monica

Andrei Lesan, Milena Adina Man, Roxana Maria Nemes, Tudor Harsovescu, Ioan Sorin Tudorache, Beatrice Mahler Boca, Carmen Monica Pop

Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation

Abstract:

Evaluation of the inflammatory response based on the Interleukin 4 and Interleukin 6 levels in patients with acquired bronchiectasis (non-cystic fibrosis) and healthy controls. The study was conducted on a group of 77 subjects, divided into 2 lots: the first lot consisting of 57 patients with acquired bronchiectasis objectified by Computed Tomography and 20 healthy individuals. The serum Interleukins 4 and 6 levels were measured using the ELISA biochemical spectrophotometry test. The results are significant from a statistical point of view, especially when it comes to the mean value of Interleukin 4 that was much higher in the control lot. Interleukin 4 is a proinflammatory cytokine and therefore we can draw the conclusion that to some extent bronchiectasis can be associated with an immunodeficiency disorder prior to the pathology itself or it can be caused by the pathology. Future research is open in this field for the analysis of interleukin levels in bronchioloalveolar lavage compared to serum levels.

Keywords:
bronchiectasis; non-cystic fibrosis; interleukins 4 and 6; anti-inflammatory; pro-inflammatory

Issue: 2019, Volume 70, Issue 7

Pages: 2410-2414

Publication date: 2019/8/15

https://doi.org/10.37358/RC.19.7.7351

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
LESAN, A., MAN, M.A., NEMES, R.M., HARSOVESCU, T., TUDORACHE, I.S., BOCA, B.M., POP, C.M., Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation, Rev. Chim., 70(7), 2019, 2410-2414.

Vancouver
Lesan A, Man MA, Nemes RM, Harsovescu T, Tudorache IS, Boca BM, Pop CM. Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation. Rev. Chim.[internet]. 2019 Jul;70(7):2410-2414. Available from: https://doi.org/10.37358/RC.19.7.7351

APA 6th edition
Lesan, A., Man, M.A., Nemes, R.M., Harsovescu, T., Tudorache, I.S., Boca, B.M. & Pop, C.M. (2019). Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation. Revista de Chimie, 70(7), 2410-2414. https://doi.org/10.37358/RC.19.7.7351

Harvard
Lesan, A., Man, M.A., Nemes, R.M., Harsovescu, T., Tudorache, I.S., Boca, B.M., Pop, C.M. (2019). 'Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation', Revista de Chimie, 70(7), pp. 2410-2414. https://doi.org/10.37358/RC.19.7.7351

IEEE
A. Lesan, M.A. Man, R.M. Nemes, T. Harsovescu, I.S. Tudorache, B.M. Boca, C.M. Pop, "Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation". Revista de Chimie, vol. 70, no. 7, pp. 2410-2414, 2019. [online]. https://doi.org/10.37358/RC.19.7.7351

Text
Andrei Lesan, Milena Adina Man, Roxana Maria Nemes, Tudor Harsovescu, Ioan Sorin Tudorache, Beatrice Mahler Boca, Carmen Monica Pop,
Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation,
Revista de Chimie,
Volume 70, Issue 7,
2019,
Pages 2410-2414,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.7.7351.
(https://revistadechimie.ro/Articles.asp?ID=7351)
Keywords: bronchiectasis; non-cystic fibrosis; interleukins 4 and 6; anti-inflammatory; pro-inflammatory

RIS
TY - JOUR
T1 - Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation
A1 - Lesan, Andrei
A2 - Man, Milena Adina
A3 - Nemes, Roxana Maria
A4 - Harsovescu, Tudor
A5 - Tudorache, Ioan Sorin
A6 - Boca, Beatrice Mahler
A7 - Pop, Carmen Monica
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 7
SP - 2410
EP - 2414
UR - https://doi.org/10.37358/RC.19.7.7351
KW - bronchiectasis
KW - non-cystic fibrosis
KW - interleukins 4 and 6
KW - anti-inflammatory
KW - pro-inflammatory
ER -

BibTex
@article{RevCh2019P2410,
author = {Lesan Andrei and Man Milena Adina and Nemes Roxana Maria and Harsovescu Tudor and Tudorache Ioan Sorin and Boca Beatrice Mahler and Pop Carmen Monica},
title = {Serum Interleukin 4 and 6 Levels Measured Using the ELISA Method in Patients with Acquired Bronchiectasis Compared to Healthy Subjects. An anti-inflammatory and pro-inflammatory relation},
journal = {Revista de Chimie},
volume = {70},
number = {7},
pages = {2410-2414},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.7.7351},
url = {https://revistadechimie.ro/Articles.asp?ID=7351}
}

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