Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes

Burcel, Miruna Gabriela; Corbu, Catalina; Coviltir, Valeria; Potop, Vasile; Constantin, Mihaela; Dascalescu, Dana; Ionescu, Catalina; Ciuluvica, Radu; Voinea, Liliana Mary

Miruna Gabriela Burcel, Catalina Corbu, Valeria Coviltir, Vasile Potop, Mihaela Constantin, Dana Dascalescu, Catalina Ionescu, Radu Ciuluvica, Liliana Mary Voinea

Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes

Abstract:

Keratoconus is a progressive ectatic disorder characterised by irregular myopic astigmatism and loss of visual acuity due to corneal thinning. Corneal collagen crosslinking is the treatment recognised to stop the progression of keratoconus. Our study evaluates and compares visibility and depth of the stromal demarcation line after corneal collagen crosslinking using anterior segment optical coherence tomography between two groups:crosslinking with dextran-based and hydroxypropyl methylcellulose-based riboflavin solutions. Our work proved a better visibility and a deeper demarcation line when we used HPMC-based riboflavin. Also the study revealed that HPMC-based riboflavin is associated with better biomechanical outcomes than dextran-based riboflavin.

Keywords:
keratoconus; crosslinking; riboflavin; demarcation line; corneal biomechanics

Issue: 2019, Volume 70, Issue 4

Pages: 1152-1156

Publication date: 2019/5/15

https://doi.org/10.37358/RC.19.4.7083

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BURCEL, M.G., CORBU, C., COVILTIR, V., POTOP, V., CONSTANTIN, M., DASCALESCU, D., IONESCU, C., CIULUVICA, R., VOINEA, L.M., Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes, Rev. Chim., 70(4), 2019, 1152-1156.

Vancouver
Burcel MG, Corbu C, Coviltir V, Potop V, Constantin M, Dascalescu D, Ionescu C, Ciuluvica R, Voinea LM. Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes. Rev. Chim.[internet]. 2019 Apr;70(4):1152-1156. Available from: https://doi.org/10.37358/RC.19.4.7083

APA 6th edition
Burcel, M.G., Corbu, C., Coviltir, V., Potop, V., Constantin, M., Dascalescu, D.,... Voinea, L.M. (2019). Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes. Revista de Chimie, 70(4), 1152-1156. https://doi.org/10.37358/RC.19.4.7083

Harvard
Burcel, M.G., Corbu, C., Coviltir, V., Potop, V., Constantin, M., Dascalescu, D., Ionescu, C., Ciuluvica, R., Voinea, L.M. (2019). 'Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes', Revista de Chimie, 70(4), pp. 1152-1156. https://doi.org/10.37358/RC.19.4.7083

IEEE
M.G. Burcel, C. Corbu, V. Coviltir, V. Potop, M. Constantin, D. Dascalescu, C. Ionescu, R. Ciuluvica, L.M. Voinea, "Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes". Revista de Chimie, vol. 70, no. 4, pp. 1152-1156, 2019. [online]. https://doi.org/10.37358/RC.19.4.7083

Text
Miruna Gabriela Burcel, Catalina Corbu, Valeria Coviltir, Vasile Potop, Mihaela Constantin, Dana Dascalescu, Catalina Ionescu, Radu Ciuluvica, Liliana Mary Voinea,
Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes,
Revista de Chimie,
Volume 70, Issue 4,
2019,
Pages 1152-1156,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.4.7083.
(https://revistadechimie.ro/Articles.asp?ID=7083)
Keywords: keratoconus; crosslinking; riboflavin; demarcation line; corneal biomechanics

RIS
TY - JOUR
T1 - Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes
A1 - Burcel, Miruna Gabriela
A2 - Corbu, Catalina
A3 - Coviltir, Valeria
A4 - Potop, Vasile
A5 - Constantin, Mihaela
A6 - Dascalescu, Dana
A7 - Ionescu, Catalina
A8 - Ciuluvica, Radu
A9 - Voinea, Liliana Mary
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 4
SP - 1152
EP - 1156
UR - https://doi.org/10.37358/RC.19.4.7083
KW - keratoconus
KW - crosslinking
KW - riboflavin
KW - demarcation line
KW - corneal biomechanics
ER -

BibTex
@article{RevCh2019P1152,
author = {Burcel Miruna Gabriela and Corbu Catalina and Coviltir Valeria and Potop Vasile and Constantin Mihaela and Dascalescu Dana and Ionescu Catalina and Ciuluvica Radu and Voinea Liliana Mary},
title = {Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes},
journal = {Revista de Chimie},
volume = {70},
number = {4},
pages = {1152-1156},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.4.7083},
url = {https://revistadechimie.ro/Articles.asp?ID=7083}
}

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