ABOUT INDEXING BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER AUTHOR'S PAGE NEWS, EVENTS CONTACT
REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
ISSN Online 2668-8212
ISSN Print: 1582-9049
ISSN-L: 1582-9049

REVISTA DE CHIMIE Latest Issue

LATEST ISSUE >>>

   Volume 75, 2024
   Volume 74, 2023
   Volume 73, 2022
   Volume 72, 2021
   Volume 71, 2020
   Volume 70, 2019
   Volume 69, 2018
   Volume 68, 2017
   Volume 67, 2016
   Volume 66, 2015
   Volume 65, 2014
   Volume 64, 2013
   Volume 63, 2012
   Volume 62, 2011
   Volume 61, 2010
   Volume 60, 2009
   Volume 59, 2008
   Volume 58, 2007
 
<<<< back

Revista de Chimie (Rev. Chim.), Year 2019, Volume 70, Issue 1, 350-354

https://doi.org/10.37358/RC.19.1.6914

Victor Vlad Costan, Anca Sava, Alexandru Carauleanu, Claudia Florida Costea, Andrei Ionut Cucu, Gabriela Dimitriu, Gabriela Florenta Dumitrescu, Nicoleta Dumitrescu, Maria Silvia Stoicescu, Gheorghe Raftu, Mihaela Dana Turliuc

Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit

Abstract:

Cavernous venous malformation (CVM) is the most common primary vascular lesion of the orbit. The aim of this study is to present authors ‘experience regarding fourteen patients with orbital CVM (so-called cavernous hemangioma) and identify their clinical and histopathological particular characteristics. From 2010 to 2017 a total of 14 patients were diagnosed with orbital cavernous hemangiomas and treated by the authors. Patients’ socio-demographic, clinical, radiological, and surgical findings were retrospectively retrieved from medical records and analyzed. Diagnosis of a cavernous hemangioma was confirmed histologically in all cases. Results: All 14 patients were females, with a mean age of 44.2 years old, ranging from 13 years to 57 years. The left orbit was affected in eleven (78.57%) cases. A painless, gradually progressive proptosis and visual disturbance were the main clinical signs. In four (28.57%) cases, the lesion was incidentally discovered at imaging evaluations for persistent headache. All patients were accurately diagnosed preoperatively based on computed tomography (CT) exam or magnetic resonance imaging (MRI). The tumors were removed successfully by anterior orbitotomy. Transconjunctival approach proved to be an important surgical procedure in their treatment, with excellent results and a low risk of complications. Histologically, all lesions revealed large vascular channels with endothelium lining and multilaminar smooth muscle layers in their walls, but also nests of small capillary channels in interstitium. No intravascular thrombosis or stromal lymphocytes could be seen. Orbital cavernous hemangiomas presented clinical, imaging and histological features of a benign lesion. Having to deal with extraconal lesions, we successfully used anterior orbitotomy, mainly the transconjuctival approach, with no complications or recurrences after a six-month follow-up period. Histologically, all lesions revealed images being most closely to dysplastic veins. So, we concluded that the so-called orbital cavernous hemangioma was rather a cavernous venous malformation.
Keywords:
orbit; cavernous hemangioma; cavernous venous malformation; histological examination

Issue: 2019, Volume 70, Issue 1
Pages: 350-354
Publication date: 2019/2/15
https://doi.org/10.37358/RC.19.1.6914
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
COSTAN, V.V., SAVA, A., CARAULEANU, A., COSTEA, C.F., CUCU, A.I., DIMITRIU, G., DUMITRESCU, G.F., DUMITRESCU, N., STOICESCU, M.S., RAFTU, G., TURLIUC, M.D., Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit, Rev. Chim., 70(1), 2019, 350-354.

Vancouver
Costan VV, Sava A, Carauleanu A, Costea CF, Cucu AI, Dimitriu G, Dumitrescu GF, Dumitrescu N, Stoicescu MS, Raftu G, Turliuc MD. Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit. Rev. Chim.[internet]. 2019 Jan;70(1):350-354. Available from: https://doi.org/10.37358/RC.19.1.6914


APA 6th edition
Costan, V.V., Sava, A., Carauleanu, A., Costea, C.F., Cucu, A.I., Dimitriu, G.,... Turliuc, M.D. (2019). Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit. Revista de Chimie, 70(1), 350-354. https://doi.org/10.37358/RC.19.1.6914


Harvard
Costan, V.V., Sava, A., Carauleanu, A., Costea, C.F., Cucu, A.I., Dimitriu, G., Dumitrescu, G.F., Dumitrescu, N., Stoicescu, M.S., Raftu, G., Turliuc, M.D. (2019). 'Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit', Revista de Chimie, 70(1), pp. 350-354. https://doi.org/10.37358/RC.19.1.6914


IEEE
V.V. Costan, A. Sava, A. Carauleanu, C.F. Costea, A.I. Cucu, G. Dimitriu, G.F. Dumitrescu, N. Dumitrescu, M.S. Stoicescu, G. Raftu, M.D. Turliuc, "Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit". Revista de Chimie, vol. 70, no. 1, pp. 350-354, 2019. [online]. https://doi.org/10.37358/RC.19.1.6914


Text
Victor Vlad Costan, Anca Sava, Alexandru Carauleanu, Claudia Florida Costea, Andrei Ionut Cucu, Gabriela Dimitriu, Gabriela Florenta Dumitrescu, Nicoleta Dumitrescu, Maria Silvia Stoicescu, Gheorghe Raftu, Mihaela Dana Turliuc,
Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit,
Revista de Chimie,
Volume 70, Issue 1,
2019,
Pages 350-354,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.1.6914.
(https://revistadechimie.ro/Articles.asp?ID=6914)
Keywords: orbit; cavernous hemangioma; cavernous venous malformation; histological examination


RIS
TY - JOUR
T1 - Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit
A1 - Costan, Victor Vlad
A2 - Sava, Anca
A3 - Carauleanu, Alexandru
A4 - Costea, Claudia Florida
A5 - Cucu, Andrei Ionut
A6 - Dimitriu, Gabriela
A7 - Dumitrescu, Gabriela Florenta
A8 - Dumitrescu, Nicoleta
A9 - Stoicescu, Maria Silvia
A10 - Raftu, Gheorghe
A11 - Turliuc, Mihaela Dana
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 1
SP - 350
EP - 354
UR - https://doi.org/10.37358/RC.19.1.6914
KW - orbit
KW - cavernous hemangioma
KW - cavernous venous malformation
KW - histological examination
ER -


BibTex
@article{RevCh2019P350,
author = {Costan Victor Vlad and Sava Anca and Carauleanu Alexandru and Costea Claudia Florida and Cucu Andrei Ionut and Dimitriu Gabriela and Dumitrescu Gabriela Florenta and Dumitrescu Nicoleta and Stoicescu Maria Silvia and Raftu Gheorghe and Turliuc Mihaela Dana},
title = {Histopathological and Clinical Characteristics of Surgically Removed Cavernous Venous Malformations (so-called Cavernous Hemangiomas) of the Orbit},
journal = {Revista de Chimie},
volume = {70},
number = {1},
pages = {350-354},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.1.6914},
url = {https://revistadechimie.ro/Articles.asp?ID=6914}
}
 
<<<< back
 
PUBLISHING SECTION
Author Guidelines
 * Paper Drafting
 * Paper Template
 * Ethical Statement
 * Paper Submission
Ghidul Autorului (ro)
Submit Paper
Author's Page
Publishing Ethics
Peer Review Process
Open Access & Archiving Policy
 Search Authors
 LATEST NEWS
REvista de Chimie NUMAR OMAGIAL PETRU PONI.. detalii
REvista de Chimie Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
dictionar English-Romanian Dictionary for Mechanical Engineering
(download pdf)
  News, Events
Crossref Member Badge
 DOI  logo
 Gold Open Access | Source=http://www.plos.org/  | Author=art designer at PLoS
Creative Commons License
 Conferences of Contemporary
 Chemistry
 Biblioteca Chimiei
 Materiale Plastice