A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment

Raducu, Laura; Cozma, Cristina Nicoleta; Stroescu, Andra Elena Balcangiu; Panduru, Mihaela; Avino, Adelaida; Tanasescu, Maria Daniela; Badita, Daniela Gabriela; Jecan, Cristian Radu

Laura Raducu, Cristina Nicoleta Cozma, Andra Elena Balcangiu Stroescu, Mihaela Panduru, Adelaida Avino, Maria Daniela Tanasescu, Daniela Gabriela Badita, Cristian Radu Jecan

A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment

Abstract:

Merkel cell carcinoma is (MCC) a rare type of skin malignancy that appears as a result of a disorganized multiplication of the Merkel cells and has a high rate of recurrence and metastases even from early stages. We describe the case of an 84-year old women diagnosed with Merkel cell carcinoma of the lower lip. Surgical treatment was realised with tumor excision and reconstruction using advancement flaps. Postoperative cosmetic and functional results were excellent, but invasion of the lateral margins, the patient’s decision of refusing re-excision and delayed radiotherapy lead to a rapid recurrence within 3 weeks. Responsiveness to subsequent radiotherapy was very good with regression of the recurrent tumor and decreasing of the local discomfort. Surgical treatment Merkel cell carcinoma of the lip is sometimes very challenging for a surgeon due to the necessity of wide resection and of the patient’s cosmetic concern. Radiotherapy remained an efficient therapy of Merkel cell carcinoma and should be used as a single or adjuvant therapy in situations where surgery cannot be applied, cisplatin chemotherapy being used for metastasis.

Keywords:
Merkel cell carcinoma; immunohistochemistry; radiotherapy; Cisplatin

Issue: 2018, Volume 69, Issue 2

Pages: 354-357

Publication date: 2018/3/15

https://doi.org/10.37358/RC.18.2.6106

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
RADUCU, L., COZMA, C.N., STROESCU, A.E.B., PANDURU, M., AVINO, A., TANASESCU, M.D., BADITA, D.G., JECAN, C.R., A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment, Rev. Chim., 69(2), 2018, 354-357.

Vancouver
Raducu L, Cozma CN, Stroescu AEB, Panduru M, Avino A, Tanasescu MD, Badita DG, Jecan CR. A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment. Rev. Chim.[internet]. 2018 Feb;69(2):354-357. Available from: https://doi.org/10.37358/RC.18.2.6106

APA 6th edition
Raducu, L., Cozma, C.N., Stroescu, A.E.B., Panduru, M., Avino, A., Tanasescu, M.D., Badita, D.G. & Jecan, C.R. (2018). A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment. Revista de Chimie, 69(2), 354-357. https://doi.org/10.37358/RC.18.2.6106

Harvard
Raducu, L., Cozma, C.N., Stroescu, A.E.B., Panduru, M., Avino, A., Tanasescu, M.D., Badita, D.G., Jecan, C.R. (2018). 'A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment', Revista de Chimie, 69(2), pp. 354-357. https://doi.org/10.37358/RC.18.2.6106

IEEE
L. Raducu, C.N. Cozma, A.E.B. Stroescu, M. Panduru, A. Avino, M.D. Tanasescu, D.G. Badita, C.R. Jecan, "A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment". Revista de Chimie, vol. 69, no. 2, pp. 354-357, 2018. [online]. https://doi.org/10.37358/RC.18.2.6106

Text
Laura Raducu, Cristina Nicoleta Cozma, Andra Elena Balcangiu Stroescu, Mihaela Panduru, Adelaida Avino, Maria Daniela Tanasescu, Daniela Gabriela Badita, Cristian Radu Jecan,
A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment,
Revista de Chimie,
Volume 69, Issue 2,
2018,
Pages 354-357,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.2.6106.
(https://revistadechimie.ro/Articles.asp?ID=6106)
Keywords: Merkel cell carcinoma; immunohistochemistry; radiotherapy; Cisplatin

RIS
TY - JOUR
T1 - A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment
A1 - Raducu, Laura
A2 - Cozma, Cristina Nicoleta
A3 - Stroescu, Andra Elena Balcangiu
A4 - Panduru, Mihaela
A5 - Avino, Adelaida
A6 - Tanasescu, Maria Daniela
A7 - Badita, Daniela Gabriela
A8 - Jecan, Cristian Radu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 2
SP - 354
EP - 357
UR - https://doi.org/10.37358/RC.18.2.6106
KW - Merkel cell carcinoma
KW - immunohistochemistry
KW - radiotherapy
KW - Cisplatin
ER -

BibTex
@article{RevCh2018P354,
author = {Raducu Laura and Cozma Cristina Nicoleta and Stroescu Andra Elena Balcangiu and Panduru Mihaela and Avino Adelaida and Tanasescu Maria Daniela and Badita Daniela Gabriela and Jecan Cristian Radu},
title = {A Rare Case of a Lower Lip Merkel Cell Carcinoma Diagnosis and treatment},
journal = {Revista de Chimie},
volume = {69},
number = {2},
pages = {354-357},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.2.6106},
url = {https://revistadechimie.ro/Articles.asp?ID=6106}
}

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