Laura Mihalache, Radu Sebastian Gavril, Lidia Iuliana Arhire, Otilia Nita, Andreea Gherasim, Andrei Catalin Oprescu, Catalina Lapuste, Daniela Constantinescu, Sergiu Serghei Padureanu, Mihai Danciu, Lucian Boiculese<br>Nutritional Biomarkers in Patients with Obesity - the Relation <br>Between Helicobacter Pylori Infection and Micronutrients

Laura Mihalache, Radu Sebastian Gavril, Lidia Iuliana Arhire, Otilia Nita, Andreea Gherasim, Andrei Catalin Oprescu, Catalina Lapuste, Daniela Constantinescu, Sergiu Serghei Padureanu, Mihai Danciu, Lucian Boiculese
Nutritional Biomarkers in Patients with Obesity - the Relation
Between Helicobacter Pylori Infection and Micronutrients

Abstract:

Obesity has experienced an epidemic evolution over the last years, affecting all age groups. Helicobacter pylori (H. pylori) infection affects over half the world’s population and the association with obesity can worsen the nutritional status of these patients. The aim of this study was to assess the nutritional biomarkers (minerals and vitamins) in obese patients in relation to H. pylori infection. Included in the study were 93 obese patients, 47 of which (50.5%) were infected with H. pylori (H. pylori present) confirmed by histology. Several clinical parameters (weight, body mass index, waist circumference and blood pressure) and nutritional biomarkers represented by micronutrients (minerals and vitamins) were analyzed. Our results showed that the levels of folic acid, total calcium and ionized calcium were higher in patients without H. pylori infection and the levels of vitamin B12, vitamin D, magnesium, serum iron and ferritin were higher in patients with H. pylori infection, but the differences were not statistically significant (p]0.05). In conclusion, in our obese patients the H. pylori infection does not influence the nutritional biomarkers represented by micronutrients (vitamins and minerals) in the evaluation of nutritional status. Keywords: nutritional biomarkers, micronutrients, obesity, Helicobacter pylori

Issue: 2016, Volume 67, Issue 12

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