ANCA MIHAELA MOCANU, CONSTANTIN LUCA, GABRIELA CIOBANU, SIMONA ISABELA DUNCA,IOAN GABRIEL SANDU, ALINA COSTINA LUCA<br>Synthesis, Characterization and Antimicrobial Activity <br>of Some New Hydrazine Metallic Complexes

ANCA MIHAELA MOCANU, CONSTANTIN LUCA, GABRIELA CIOBANU, SIMONA ISABELA DUNCA,IOAN GABRIEL SANDU, ALINA COSTINA LUCA
Synthesis, Characterization and Antimicrobial Activity
of Some New Hydrazine Metallic Complexes

Abstract:

The present paper reports the results of the studies on the synthesis of new metallic complexes obtained by the condensation of the hydrazides of sulphonamidated aryloxyalkyl-carboxylic acids with various chlorides and acetates of transitional metals resulting in final products with potential anti-tumour, anti-oxidative, anti-tubercular and herbicidal and growing regulators properties. These compounds were properly characterized by both physico-chemical methods (elemental analysis) and IR, 1NMR, 13C-NMR, GC-MS and UV-Vis spectral measurements. The obtained data gave useful information about the coordination way of the metallic ion, the atoms involved in the bonds between the central ion and ligands and also about the purity of the final compounds. Since actually an increasing number of complex combinations are largely applied in anti-microbial therapy the above mentioned complexes were tested for their antimicrobial action on certain gram negative (Escherichia coli, Pseudomonas aeruginosa), and gram positive (Staphyloccocus aureus) germs and on yeasts (Candida albicans). Keywords: hydrazide, metallic complexes, antimicrobial action, tested activity, spectral measurements

Issue: 2015, Volume 66, Issue 8

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