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Revista de Chimie (Rev. Chim.), Year 2009, Volume 60, Issue 9,





ALEXANDRU WOINAROSCHY, SANDU TARAS
Simulation and Optimization of Citric Acid Production
with SuperPro Designer using a Client-Server Interface

Abstract:

SuperPro Designer is a very useful simulator due to its large data bases of specific chemical compounds and unit operations, and for the evaluation of economical and ecological process performance indexes. For sensitivity analysis and optimization purposes, hundreds or more simulations are necessary. Consequently, an off-line use of the simulator isn’t possible. A client-server interface based on Component Object Module (COM) technology using Excel-Visual Basic for Applications (VBA) scripts was developed in order to call SuperPro Designer simulator repetitively, inside loops, for various sets of input variables. The potential of the client-server application was demonstrated in the frame of the sensitivity analysis and optimization of the bioprocesses of citric acid production from starch fermentation using Aspergillus niger. The corresponding results are useful both for technological, and economical reasons. Keywords: biochemical processes, simulation, optimization


Issue: 2009, Volume 60, Issue 9
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