Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms

Ichim, Daniela Luminita; Duceac, Letitia Doina; Marcu, Constantin; Iordache, Alin Constantin; Ciomaga, Irina Mihaela; Luca, Alina Costina; Goroftei, Elena Roxana Bogdan; Mitrea, Geta; Damir, Daniela; Stafie, Liviu

Daniela Luminita Ichim, Letitia Doina Duceac, Constantin Marcu, Alin Constantin Iordache, Irina Mihaela Ciomaga, Alina Costina Luca, Elena Roxana Bogdan Goroftei, Geta Mitrea, Daniela Damir, Liviu Stafie

Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms

Abstract:

Some infectious agents frequently act on human body. Multi-drug resistant microorganisms (MDR) develop the capacity to stabilize biofilms. The use of antimicrobials loaded nanoparticles can defeat antibiotic resistance mechanism. The major aim of this study was the synthesis and physico-chemical characterization of Colistin molecules intercalated nanoparticles in order to enhance antibiotic efficacy against multi-drug resistant microorganisms. Advanced characterization techniques were used to analyze new nanostructures containing antibiotics in order to improve antimicrobial efficacy of the free drug. Nano-encapsulated Colistin is presumed to be more efficient in the eradication of severe infections caused by MDR.

Keywords:
nanoparticles; Colistin; infection; sepsis; pediatrics; epidemiology; neurosurgery; cardiology; pulmonology

Issue: 2019, Volume 70, Issue 10

Pages: 3734-3737

Publication date: 2019/11/15

https://doi.org/10.37358/RC.19.10.7635

Download Pdf Article

This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ICHIM, D.L., DUCEAC, L.D., MARCU, C., IORDACHE, A.C., CIOMAGA, I.M., LUCA, A.C., GOROFTEI, E.R.B., MITREA, G., DAMIR, D., STAFIE, L., Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms, Rev. Chim., 70(10), 2019, 3734-3737.

Vancouver
Ichim DL, Duceac LD, Marcu C, Iordache AC, Ciomaga IM, Luca AC, Goroftei ERB, Mitrea G, Damir D, Stafie L. Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms. Rev. Chim.[internet]. 2019 Oct;70(10):3734-3737. Available from: https://doi.org/10.37358/RC.19.10.7635

APA 6th edition
Ichim, D.L., Duceac, L.D., Marcu, C., Iordache, A.C., Ciomaga, I.M., Luca, A.C.,... Stafie, L. (2019). Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms. Revista de Chimie, 70(10), 3734-3737. https://doi.org/10.37358/RC.19.10.7635

Harvard
Ichim, D.L., Duceac, L.D., Marcu, C., Iordache, A.C., Ciomaga, I.M., Luca, A.C., Goroftei, E.R.B., Mitrea, G., Damir, D., Stafie, L. (2019). 'Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms', Revista de Chimie, 70(10), pp. 3734-3737. https://doi.org/10.37358/RC.19.10.7635

IEEE
D.L. Ichim, L.D. Duceac, C. Marcu, A.C. Iordache, I.M. Ciomaga, A.C. Luca, E.R.B. Goroftei, G. Mitrea, D. Damir, L. Stafie, "Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms". Revista de Chimie, vol. 70, no. 10, pp. 3734-3737, 2019. [online]. https://doi.org/10.37358/RC.19.10.7635

Text
Daniela Luminita Ichim, Letitia Doina Duceac, Constantin Marcu, Alin Constantin Iordache, Irina Mihaela Ciomaga, Alina Costina Luca, Elena Roxana Bogdan Goroftei, Geta Mitrea, Daniela Damir, Liviu Stafie,
Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms,
Revista de Chimie,
Volume 70, Issue 10,
2019,
Pages 3734-3737,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.10.7635.
(https://revistadechimie.ro/Articles.asp?ID=7635)
Keywords: nanoparticles; Colistin; infection; sepsis; pediatrics; epidemiology; neurosurgery; cardiology; pulmonology

RIS
TY - JOUR
T1 - Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms
A1 - Ichim, Daniela Luminita
A2 - Duceac, Letitia Doina
A3 - Marcu, Constantin
A4 - Iordache, Alin Constantin
A5 - Ciomaga, Irina Mihaela
A6 - Luca, Alina Costina
A7 - Goroftei, Elena Roxana Bogdan
A8 - Mitrea, Geta
A9 - Damir, Daniela
A10 - Stafie, Liviu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 10
SP - 3734
EP - 3737
UR - https://doi.org/10.37358/RC.19.10.7635
KW - nanoparticles
KW - Colistin
KW - infection
KW - sepsis
KW - pediatrics
KW - epidemiology
KW - neurosurgery
KW - cardiology
KW - pulmonology
ER -

BibTex
@article{RevCh2019P3734,
author = {Ichim Daniela Luminita and Duceac Letitia Doina and Marcu Constantin and Iordache Alin Constantin and Ciomaga Irina Mihaela and Luca Alina Costina and Goroftei Elena Roxana Bogdan and Mitrea Geta and Damir Daniela and Stafie Liviu},
title = {Synthesis and Characterization of Colistin Loaded Nanoparticles Used to Combat Multi-drug Resistant Microorganisms},
journal = {Revista de Chimie},
volume = {70},
number = {10},
pages = {3734-3737},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.10.7635},
url = {https://revistadechimie.ro/Articles.asp?ID=7635}
}

<<<< back

PUBLISHING SECTION

Author Guidelines

* Paper Drafting

* Paper Template

* Ethical Statement

* Paper Submission

Ghidul Autorului (ro)

Open Access & Archiving Policy

Search Authors

LATEST NEWS
	NUMAR OMAGIAL PETRU PONI.. detalii
	Revista de Chimie - 70 de ani de aparitie neintrerupta.. detalii
	English-Romanian Dictionary for Mechanical Engineering (download pdf)

News, Events

Gold Open Access | Source=http://www.plos.org/ | Author=art designer at PLoS

Conferences of Contemporary
Chemistry

Biblioteca Chimiei

Materiale Plastice

REVISTA DE CHIMIE

About

Board

Indexing