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REVISTA DE CHIMIE
Cite as: Rev. Chim.
https://doi.org/10.37358/Rev.Chim.1949

OSIM Nr. R102355
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Revista de Chimie (Rev. Chim.), Year 2016, Volume 67, Issue 1,



Bogdan Tita, Claudiu Morgovan, Dumitru Tita, Teodora Alina Neag

Anti-inflammatory Drugs Interacting with Zn(II) Metal Ion. Synthesis, characterization and thermal behaviour of the complex with ketoprofen

Abstract:

A complex of Zn(II) metal ion with the anti-inflammatory drug, 2-(3-benzoylphenyl)-propionic acid (Ketoprofen) was isolated and investigated. The complex was characterized by elemental analysis, Fourier transformed infrared spectroscopy (FT-IR), X-ray diffraction powder (XRPD) and thermal analysis.The thermal behavior was studied by TG/DTG and DTA methods under non-isothermal conditions in a dynamic air atmosphere. The results provided informations of the composition, structure, thermal behavior, dehydration and thermal decomposition. The spectroscopic study suggest that the carboxylate group of ketoprofen is coordinate to metal as bidentate bond.
Keywords:
anti-inflammatory drug; ketoprofen; FT-IR spectroscopy; X-ray analysis; thermal analysis

Issue: 2016, Volume 67, Issue 1
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