Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight

Alexescu, Teodora Gabriela; Bordea, Ioana Roxana; Cozma, Angela; Rajnoveanu, Ruxandra; Buzoianu, Anca Dana; Nemes, Roxana Maria; Tudorache, Sorin Ioan; Boca, Beatrice Mahler; Todea, Doina Adina

Teodora Gabriela Alexescu, Ioana Roxana Bordea, Angela Cozma, Ruxandra Rajnoveanu, Anca Dana Buzoianu, Roxana Maria Nemes, Sorin Ioan Tudorache, Beatrice Mahler Boca, Doina Adina Todea

Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight

Abstract:

Obesity and Overweight have the highest rate of incidence and prevalence in the past 3 decades, as global pathologies. The purpose of this study was to evaluate cardiovascular, classic and modern risk factors in overweight and obese patients by studying lipid metabolism (total cholesterol, HDL-cholesterol, non-HDL-cholesterol, LDL-cholesterol, serum triglycerides), glucose metabolism, insulin resistance and insulin sensitivity, the prevalence of hypertension (HBP) and the prevalence of metabolic syndrome (MS). This analytical study was performed on 111 subjects divided as follows: Group I consisting of 27 normal weight subjects - NW; Group II consisting of 84 overweight and obese subjects - OW + O: 36 overweight patients - OW; 33 patients with grade I obesity - O-I; 13 patients with grade II obesity - O-II; 2 patients with grade III obesity - O-III. The overweight and obese, although unknown with heart disease, have significant metabolic changes, such as atherogenic dyslipidemia, dysglycemia, high insulin resistance and low insulin sensitivity, metabolic syndrome, these being the first steps towards endothelial dysfunction and early atherosclerosis.

Keywords:
obesity; metabolism changes; insulinoresistance; overweight

Issue: 2019, Volume 70, Issue 10

Pages: 3627-3633

Publication date: 2019/11/15

https://doi.org/10.37358/RC.19.10.7610

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ALEXESCU, T.G., BORDEA, I.R., COZMA, A., RAJNOVEANU, R., BUZOIANU, A.D., NEMES, R.M., TUDORACHE, S.I., BOCA, B.M., TODEA, D.A., Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight, Rev. Chim., 70(10), 2019, 3627-3633.

Vancouver
Alexescu TG, Bordea IR, Cozma A, Rajnoveanu R, Buzoianu AD, Nemes RM, Tudorache SI, Boca BM, Todea DA. Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight. Rev. Chim.[internet]. 2019 Oct;70(10):3627-3633. Available from: https://doi.org/10.37358/RC.19.10.7610

APA 6th edition
Alexescu, T.G., Bordea, I.R., Cozma, A., Rajnoveanu, R., Buzoianu, A.D., Nemes, R.M.,... Todea, D.A. (2019). Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight. Revista de Chimie, 70(10), 3627-3633. https://doi.org/10.37358/RC.19.10.7610

Harvard
Alexescu, T.G., Bordea, I.R., Cozma, A., Rajnoveanu, R., Buzoianu, A.D., Nemes, R.M., Tudorache, S.I., Boca, B.M., Todea, D.A. (2019). 'Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight', Revista de Chimie, 70(10), pp. 3627-3633. https://doi.org/10.37358/RC.19.10.7610

IEEE
T.G. Alexescu, I.R. Bordea, A. Cozma, R. Rajnoveanu, A.D. Buzoianu, R.M. Nemes, S.I. Tudorache, B.M. Boca, D.A. Todea, "Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight". Revista de Chimie, vol. 70, no. 10, pp. 3627-3633, 2019. [online]. https://doi.org/10.37358/RC.19.10.7610

Text
Teodora Gabriela Alexescu, Ioana Roxana Bordea, Angela Cozma, Ruxandra Rajnoveanu, Anca Dana Buzoianu, Roxana Maria Nemes, Sorin Ioan Tudorache, Beatrice Mahler Boca, Doina Adina Todea,
Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight,
Revista de Chimie,
Volume 70, Issue 10,
2019,
Pages 3627-3633,
ISSN 2668-8212,
https://doi.org/10.37358/RC.19.10.7610.
(https://revistadechimie.ro/Articles.asp?ID=7610)
Keywords: obesity; metabolism changes; insulinoresistance; overweight

RIS
TY - JOUR
T1 - Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight
A1 - Alexescu, Teodora Gabriela
A2 - Bordea, Ioana Roxana
A3 - Cozma, Angela
A4 - Rajnoveanu, Ruxandra
A5 - Buzoianu, Anca Dana
A6 - Nemes, Roxana Maria
A7 - Tudorache, Sorin Ioan
A8 - Boca, Beatrice Mahler
A9 - Todea, Doina Adina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2019
VL - 70
IS - 10
SP - 3627
EP - 3633
UR - https://doi.org/10.37358/RC.19.10.7610
KW - obesity
KW - metabolism changes
KW - insulinoresistance
KW - overweight
ER -

BibTex
@article{RevCh2019P3627,
author = {Alexescu Teodora Gabriela and Bordea Ioana Roxana and Cozma Angela and Rajnoveanu Ruxandra and Buzoianu Anca Dana and Nemes Roxana Maria and Tudorache Sorin Ioan and Boca Beatrice Mahler and Todea Doina Adina},
title = {Metabolic Profile and the Risk of Early Atherosclerosis in Patients with Obesity and Overweight},
journal = {Revista de Chimie},
volume = {70},
number = {10},
pages = {3627-3633},
year = {2019},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.19.10.7610},
url = {https://revistadechimie.ro/Articles.asp?ID=7610}
}

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