Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea

Stefanescu, Dragos Cristian; Hainarosie, Razvan; Zainea, Viorel

Dragos Cristian Stefanescu, Razvan Hainarosie, Viorel Zainea

Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea

Abstract:

Although it seems to be an exhausted subject at first glance, the therapeutic approach in obstructive sleep apnea syndrome (O.S.A.S.) is still an open subject. The continuous positive airway pressure (C.P.A.P.) represents the gold standard of therapy in O.S.A.S. However, this therapeutic process with C.P.A.P. has a low rate of compliancy, over 50% of patients quit in the first year of use. Implicitly, surgical solutions or mandibular advancement devices remain an alternative for many of these patients. High costs, complexity and risks associated with surgery have led to the identification of more accurate methods for topographic and functional diagnosis in O.S.A.S. Drug-induced sleep endoscopy (D.I.S.E.) with target-controlled infusion (T.C.I.) using propofol in the management of patients with obstructive sleep apnea is a relatively recently introduced method in Romania. The present paper describes our experience with D.I.S.E for selected patients, who have undergone surgery on the upper airway for O.S.A.S. The D.I.S.E method has led to the modification of the initial surgical plan in over 60% of patients with multi-level obstruction. Under these conditions, the surgical success rate in patients of the study increased to 80% at 6 months. Considering the specific endowment of each tertiary sleep center, the presence or absence of an operator block and the anesthetist’s experience with target-controlled (T.C.I.) infusion using propofol, more extensive and multicenter studies are needed for standardization of D.I.S.E.

Keywords:
drug-induced sleep endoscopy; sleep disorders; propofol

Issue: 2018, Volume 69, Issue 6

Pages: 1431-1434

Publication date: 2018/7/15

https://doi.org/10.37358/RC.18.6.6340

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
STEFANESCU, D.C., HAINAROSIE, R., ZAINEA, V., Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea, Rev. Chim., 69(6), 2018, 1431-1434.

Vancouver
Stefanescu DC, Hainarosie R, Zainea V. Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea. Rev. Chim.[internet]. 2018 Jun;69(6):1431-1434. Available from: https://doi.org/10.37358/RC.18.6.6340

APA 6th edition
Stefanescu, D.C., Hainarosie, R. & Zainea, V. (2018). Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea. Revista de Chimie, 69(6), 1431-1434. https://doi.org/10.37358/RC.18.6.6340

Harvard
Stefanescu, D.C., Hainarosie, R., Zainea, V. (2018). 'Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea', Revista de Chimie, 69(6), pp. 1431-1434. https://doi.org/10.37358/RC.18.6.6340

IEEE
D.C. Stefanescu, R. Hainarosie, V. Zainea, "Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea". Revista de Chimie, vol. 69, no. 6, pp. 1431-1434, 2018. [online]. https://doi.org/10.37358/RC.18.6.6340

Text
Dragos Cristian Stefanescu, Razvan Hainarosie, Viorel Zainea,
Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea,
Revista de Chimie,
Volume 69, Issue 6,
2018,
Pages 1431-1434,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.6.6340.
(https://revistadechimie.ro/Articles.asp?ID=6340)
Keywords: drug-induced sleep endoscopy; sleep disorders; propofol

RIS
TY - JOUR
T1 - Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea
A1 - Stefanescu, Dragos Cristian
A2 - Hainarosie, Razvan
A3 - Zainea, Viorel
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 6
SP - 1431
EP - 1434
UR - https://doi.org/10.37358/RC.18.6.6340
KW - drug-induced sleep endoscopy
KW - sleep disorders
KW - propofol
ER -

BibTex
@article{RevCh2018P1431,
author = {Stefanescu Dragos Cristian and Hainarosie Razvan and Zainea Viorel},
title = {Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea},
journal = {Revista de Chimie},
volume = {69},
number = {6},
pages = {1431-1434},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.6.6340},
url = {https://revistadechimie.ro/Articles.asp?ID=6340}
}

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