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REVISTA DE CHIMIE
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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2018, Volume 69, Issue 4, 1002-1005

https://doi.org/10.37358/RC.18.4.6246

Cristian Romanec, Mariana Pacurar, Mioara Decusara, Monica Mihaela Scutariu, Delia Hinganu, Marius Valeriu Hinganu, Corina Ciupilan

Labio-palatine Cleft, Morphological Substrate

Abstract:

Labio-palatin clefts are the most common type of craniofacial malformation encountered in practice and among the most common congenital abnormalities; it represent morphological and functional defects in newborns caused by genetically changes or environmental factors; those of the cervico-facial region have an increased incidence due to local embryological complexity and multifactorial etiology. The anomaly, with its variants, results from an inherent defect between the internal and external nasal buds, both from the frontal and upper maxillary bud. Labio-palatine clefts are characterized by a tissue deficiency as well as an abnormal disposition of the present tissues. It is believed that the labial clefts are consecutive to the lack of apoptosis of the ectoderm which envelops the internal maxillary and nasal buds, thus constituting a barrier to the fusion process of buds. Depending on the location and the extentension of the cleft, the labial cleft occurs, or the more frequent, the labial-alveolar cleft. The study group consisted of 22 patients with labio-palatine clefts, of which 16 boys (72.72%) and 6 girls (27.27%), who presented in the clinic for treatment. When the causative factor acts earlier, the clfet develops posteriorly, since mesodermization begins from the posterior to the anterior. The more disturbing factor acts, the greater the cleft. The increase in the incidence of labial-palatine cleft is believed to be mainly due to the increase in the number of women of older gestational age in women; women over 35 years of age have a double risk of having children with labio-palatine clefts, the risk being three times higher for mothers over the 39 years.
Keywords:
labi-palatine clefts; medical recovery; complex treatment

Issue: 2018, Volume 69, Issue 4
Pages: 1002-1005
Publication date: 2018/5/15
https://doi.org/10.37358/RC.18.4.6246
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
ROMANEC, C., PACURAR, M., DECUSARA, M., SCUTARIU, M.M., HINGANU, D., HINGANU, M.V., CIUPILAN, C., Labio-palatine Cleft, Morphological Substrate, Rev. Chim., 69(4), 2018, 1002-1005.

Vancouver
Romanec C, Pacurar M, Decusara M, Scutariu MM, Hinganu D, Hinganu MV, Ciupilan C. Labio-palatine Cleft, Morphological Substrate. Rev. Chim.[internet]. 2018 Apr;69(4):1002-1005. Available from: https://doi.org/10.37358/RC.18.4.6246


APA 6th edition
Romanec, C., Pacurar, M., Decusara, M., Scutariu, M.M., Hinganu, D., Hinganu, M.V. & Ciupilan, C. (2018). Labio-palatine Cleft, Morphological Substrate. Revista de Chimie, 69(4), 1002-1005. https://doi.org/10.37358/RC.18.4.6246


Harvard
Romanec, C., Pacurar, M., Decusara, M., Scutariu, M.M., Hinganu, D., Hinganu, M.V., Ciupilan, C. (2018). 'Labio-palatine Cleft, Morphological Substrate', Revista de Chimie, 69(4), pp. 1002-1005. https://doi.org/10.37358/RC.18.4.6246


IEEE
C. Romanec, M. Pacurar, M. Decusara, M.M. Scutariu, D. Hinganu, M.V. Hinganu, C. Ciupilan, "Labio-palatine Cleft, Morphological Substrate". Revista de Chimie, vol. 69, no. 4, pp. 1002-1005, 2018. [online]. https://doi.org/10.37358/RC.18.4.6246


Text
Cristian Romanec, Mariana Pacurar, Mioara Decusara, Monica Mihaela Scutariu, Delia Hinganu, Marius Valeriu Hinganu, Corina Ciupilan,
Labio-palatine Cleft, Morphological Substrate,
Revista de Chimie,
Volume 69, Issue 4,
2018,
Pages 1002-1005,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.4.6246.
(https://revistadechimie.ro/Articles.asp?ID=6246)
Keywords: labi-palatine clefts; medical recovery; complex treatment


RIS
TY - JOUR
T1 - Labio-palatine Cleft, Morphological Substrate
A1 - Romanec, Cristian
A2 - Pacurar, Mariana
A3 - Decusara, Mioara
A4 - Scutariu, Monica Mihaela
A5 - Hinganu, Delia
A6 - Hinganu, Marius Valeriu
A7 - Ciupilan, Corina
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 4
SP - 1002
EP - 1005
UR - https://doi.org/10.37358/RC.18.4.6246
KW - labi-palatine clefts
KW - medical recovery
KW - complex treatment
ER -


BibTex
@article{RevCh2018P1002,
author = {Romanec Cristian and Pacurar Mariana and Decusara Mioara and Scutariu Monica Mihaela and Hinganu Delia and Hinganu Marius Valeriu and Ciupilan Corina},
title = {Labio-palatine Cleft, Morphological Substrate},
journal = {Revista de Chimie},
volume = {69},
number = {4},
pages = {1002-1005},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.4.6246},
url = {https://revistadechimie.ro/Articles.asp?ID=6246}
}
 
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