Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro

Pinzariu, Alin Constantin; Oboroceanu, Teodor; Eloae, Florin Zugun; Hristov, Ioana; Costan, Victor Vlad; Labusca, Luminita; Cianga, Petru; Verestiuc, Liliana; Hanganu, Bianca; Crauciuc, Dragos Valentin; Manoilescu, Irina Smaranda; Sindilar, Eusebiu Viorel; Mocanu, Veronica

Alin Constantin Pinzariu, Teodor Oboroceanu, Florin Zugun Eloae, Ioana Hristov, Victor Vlad Costan, Luminita Labusca, Petru Cianga, Liliana Verestiuc, Bianca Hanganu, Dragos Valentin Crauciuc, Irina Smaranda Manoilescu, Eusebiu Viorel Sindilar, Veronica Mocanu

Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro

Abstract:

The age-associated adiposity and the effect of long-term vitamin D was studied in vitamin D deficient rats. In in vivo experiments, the influence of a 9 months of vitamin D treatment (weekly oral gavage with 0.125 mg vitamin D3 (5000 IU)/100g body weight) on the adipocyte precursors from the omental adipose tissue was examinated. In in vitro experiment, rat adipose-derived mesenchymal stromal/stem cells (ASCs) were induced to differentiate into adipocytes in the presence or absence of 25(OH)D3 (0.25, 25, and 2500 nmol/L). ASCs derived from vitamin D-treated animals showed an increase adipogenic potential as compared to vitamin D-deficient rats. The addition of 25(OH)D3 inhibits the adipocyte differentiation and lipid deposition in a dose dependent manner.

Keywords:
vitamin D; sarcopenia; adipocyte precursors; adipose-derived mesenchymal stromal/stem cells

Issue: 2018, Volume 69, Issue 3

Pages: 731-734

Publication date: 2018/4/15

https://doi.org/10.37358/RC.18.3.6187

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
PINZARIU, A.C., OBOROCEANU, T., ELOAE, F.Z., HRISTOV, I., COSTAN, V.V., LABUSCA, L., CIANGA, P., VERESTIUC, L., HANGANU, B., CRAUCIUC, D.V., MANOILESCU, I.S., SINDILAR, E.V., MOCANU, V., Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro, Rev. Chim., 69(3), 2018, 731-734.

Vancouver
Pinzariu AC, Oboroceanu T, Eloae FZ, Hristov I, Costan VV, Labusca L, Cianga P, Verestiuc L, Hanganu B, Crauciuc DV, Manoilescu IS, Sindilar EV, Mocanu V. Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro. Rev. Chim.[internet]. 2018 Mar;69(3):731-734. Available from: https://doi.org/10.37358/RC.18.3.6187

APA 6th edition
Pinzariu, A.C., Oboroceanu, T., Eloae, F.Z., Hristov, I., Costan, V.V., Labusca, L.,... Mocanu, V. (2018). Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro. Revista de Chimie, 69(3), 731-734. https://doi.org/10.37358/RC.18.3.6187

Harvard
Pinzariu, A.C., Oboroceanu, T., Eloae, F.Z., Hristov, I., Costan, V.V., Labusca, L., Cianga, P., Verestiuc, L., Hanganu, B., Crauciuc, D.V., Manoilescu, I.S., Sindilar, E.V., Mocanu, V. (2018). 'Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro', Revista de Chimie, 69(3), pp. 731-734. https://doi.org/10.37358/RC.18.3.6187

IEEE
A.C. Pinzariu, T. Oboroceanu, F.Z. Eloae, I. Hristov, V.V. Costan, L. Labusca, P. Cianga, L. Verestiuc, B. Hanganu, D.V. Crauciuc, I.S. Manoilescu, E.V. Sindilar, V. Mocanu, "Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro". Revista de Chimie, vol. 69, no. 3, pp. 731-734, 2018. [online]. https://doi.org/10.37358/RC.18.3.6187

Text
Alin Constantin Pinzariu, Teodor Oboroceanu, Florin Zugun Eloae, Ioana Hristov, Victor Vlad Costan, Luminita Labusca, Petru Cianga, Liliana Verestiuc, Bianca Hanganu, Dragos Valentin Crauciuc, Irina Smaranda Manoilescu, Eusebiu Viorel Sindilar, Veronica Mocanu,
Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro,
Revista de Chimie,
Volume 69, Issue 3,
2018,
Pages 731-734,
ISSN 2668-8212,
https://doi.org/10.37358/RC.18.3.6187.
(https://revistadechimie.ro/Articles.asp?ID=6187)
Keywords: vitamin D; sarcopenia; adipocyte precursors; adipose-derived mesenchymal stromal/stem cells

RIS
TY - JOUR
T1 - Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro
A1 - Pinzariu, Alin Constantin
A2 - Oboroceanu, Teodor
A3 - Eloae, Florin Zugun
A4 - Hristov, Ioana
A5 - Costan, Victor Vlad
A6 - Labusca, Luminita
A7 - Cianga, Petru
A8 - Verestiuc, Liliana
A9 - Hanganu, Bianca
A10 - Crauciuc, Dragos Valentin
A11 - Manoilescu, Irina Smaranda
A12 - Sindilar, Eusebiu Viorel
A13 - Mocanu, Veronica
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2018
VL - 69
IS - 3
SP - 731
EP - 734
UR - https://doi.org/10.37358/RC.18.3.6187
KW - vitamin D
KW - sarcopenia
KW - adipocyte precursors
KW - adipose-derived mesenchymal stromal/stem cells
ER -

BibTex
@article{RevCh2018P731,
author = {Pinzariu Alin Constantin and Oboroceanu Teodor and Eloae Florin Zugun and Hristov Ioana and Costan Victor Vlad and Labusca Luminita and Cianga Petru and Verestiuc Liliana and Hanganu Bianca and Crauciuc Dragos Valentin and Manoilescu Irina Smaranda and Sindilar Eusebiu Viorel and Mocanu Veronica},
title = {Vitamin D as a Regulator of Adipocyte Differentiation Effects in vivo and in vitro},
journal = {Revista de Chimie},
volume = {69},
number = {3},
pages = {731-734},
year = {2018},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.18.3.6187},
url = {https://revistadechimie.ro/Articles.asp?ID=6187}
}

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