Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus

Georgescu, Simona Roxana; Ene, Corina Daniela; Nicolae, Ilinca; Mitran, Madalina; Musetescu, Alina; Matei, Clara; Rusu, Laura Cristina; Tampa, Mircea

Simona Roxana Georgescu, Corina Daniela Ene, Ilinca Nicolae, Madalina Mitran, Alina Musetescu, Clara Matei, Laura Cristina Rusu, Mircea Tampa

Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus

Abstract:

Reflectometric technique for analyzing urine strips represents a simple, fast and inexpensive method, with no risk and discomfort for the patient. In the present paper, the authors conducted a retrospective study on the possible association between lichen planus (LP) and a number of pathological conditions that produce changes of urine metabolites. A retrospective study was made on 77 patients with LP (49 cases of cutaneous LP - CLP, 28 cases of oral LP - OLP) who were diagnosed and treated in the dermatology department of Victor Babes Hospital for Infectious and Tropical Diseases. The quantification of certain urine metabolites in the spontaneous urine through reflectometric technique may reveal liver diseases (urobilinogen, bilirubin), kidney diseases (erythrocytes, proteins, albumin, creatinine, albumin/creatinine ratio, urine specific gravity, pH), metabolic disorders (glucose, ketones, pH, ascorbic acid) and urinary diseases (leucocyturia, nitrites, proteins, erythrocytes). The evaluation of the patients included clinical examination and laboratory and imaging tests. Among the investigated patients with LP we found: 16 cases of hepatic dysfunction (20.8%), 7 cases of renal dysfunction (9.1%), 11 cases of metabolic disorders (14.3%) and 14 cases of urinary tract infections (18.2%). No differences were found between patients with cutaneous and oral LP. The linear regression analysis revealed: positive association between concentrations of urobilinogen and bilirubin (r = 0.174, p = 0.044), negative association between albumin and creatinine (r = -0.316, p = 0.007), positive association between glucose and ketones (r = 0.266, p = 0.098) and positive association between leucocyturia and urine nitrite levels (r = 0.202, p = 0.050). Based on clinical and laboratory data, 85.7% of results obtained from urine biochemistry were confirmed. This analysis did not find any difference between patients with cutaneous and oral LP. By determining a full panel of urine metabolites through reflectometric analysis we were able to identify the main pathological changes in patients with LP.

Keywords:
test strips; reflectance photometer; lichen planus

Issue: 2017, Volume 68, Issue 5

Pages: 1103-1108

Publication date: 2017/6/15

https://doi.org/10.37358/RC.17.5.5621

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GEORGESCU, S.R., ENE, C.D., NICOLAE, I., MITRAN, M., MUSETESCU, A., MATEI, C., RUSU, L.C., TAMPA, M., Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus, Rev. Chim., 68(5), 2017, 1103-1108.

Vancouver
Georgescu SR, Ene CD, Nicolae I, Mitran M, Musetescu A, Matei C, Rusu LC, Tampa M. Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus. Rev. Chim.[internet]. 2017 May;68(5):1103-1108. Available from: https://doi.org/10.37358/RC.17.5.5621

APA 6th edition
Georgescu, S.R., Ene, C.D., Nicolae, I., Mitran, M., Musetescu, A., Matei, C., Rusu, L.C. & Tampa, M. (2017). Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus. Revista de Chimie, 68(5), 1103-1108. https://doi.org/10.37358/RC.17.5.5621

Harvard
Georgescu, S.R., Ene, C.D., Nicolae, I., Mitran, M., Musetescu, A., Matei, C., Rusu, L.C., Tampa, M. (2017). 'Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus', Revista de Chimie, 68(5), pp. 1103-1108. https://doi.org/10.37358/RC.17.5.5621

IEEE
S.R. Georgescu, C.D. Ene, I. Nicolae, M. Mitran, A. Musetescu, C. Matei, L.C. Rusu, M. Tampa, "Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus". Revista de Chimie, vol. 68, no. 5, pp. 1103-1108, 2017. [online]. https://doi.org/10.37358/RC.17.5.5621

Text
Simona Roxana Georgescu, Corina Daniela Ene, Ilinca Nicolae, Madalina Mitran, Alina Musetescu, Clara Matei, Laura Cristina Rusu, Mircea Tampa,
Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus,
Revista de Chimie,
Volume 68, Issue 5,
2017,
Pages 1103-1108,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.5.5621.
(https://revistadechimie.ro/Articles.asp?ID=5621)
Keywords: test strips; reflectance photometer; lichen planus

RIS
TY - JOUR
T1 - Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus
A1 - Georgescu, Simona Roxana
A2 - Ene, Corina Daniela
A3 - Nicolae, Ilinca
A4 - Mitran, Madalina
A5 - Musetescu, Alina
A6 - Matei, Clara
A7 - Rusu, Laura Cristina
A8 - Tampa, Mircea
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 5
SP - 1103
EP - 1108
UR - https://doi.org/10.37358/RC.17.5.5621
KW - test strips
KW - reflectance photometer
KW - lichen planus
ER -

BibTex
@article{RevCh2017P1103,
author = {Georgescu Simona Roxana and Ene Corina Daniela and Nicolae Ilinca and Mitran Madalina and Musetescu Alina and Matei Clara and Rusu Laura Cristina and Tampa Mircea},
title = {Reflectometric Analysis for Identification of Various Pathological Conditions Associated with Lichen Planus},
journal = {Revista de Chimie},
volume = {68},
number = {5},
pages = {1103-1108},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.5.5621},
url = {https://revistadechimie.ro/Articles.asp?ID=5621}
}

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