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https://doi.org/10.37358/Rev.Chim.1949

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Revista de Chimie (Rev. Chim.), Year 2017, Volume 68, Issue 5, 1028-1030

https://doi.org/10.37358/RC.17.5.5604

Paul Dan Sirbu, Razvan Tudor, Oana Viola Badulescu

Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients

Abstract:

Type A hemophilia is a hereditary coagulopathy caused by coagulation factor VIII deficiency, clinically characterized by hemorrhagiparous phenomena of different intensity, depending on disease severity or on the intensity of the injury suffered by the patient. The severe forms of the condition may become complicated by spontaneous sometimes even life-threatening bleeding, in the absence of factor VIII substitution treatment. Considerable bleeding may occur at the intraarticular, intramuscular or mucosa level, whereas life-threatening bleeding may occur anywhere in severe injuries. Two types of hemorrhagiparous are specific to the disease and are also the most common: hemarthroses and hematomas. As far as hemarthroses are concerned, each joint hemorrhage episode causes a topical disorder, which predisposes to recurrence, with the onset over time of the main chronic complication of this condition, hemophilic athropathy, which progresses slowly throughout the patient’s life and generates severe sequellae (ankylosis). This paper aims at emphasizing the importance of viscosupplementation by the injection of hyaluronic acid and chondroitin sulfate in the joints of hemophilic patients with severe athropathy, with a view to improving the locomotor function, to reducing the number of bleeding episodes and joint pain.
Keywords:
hemophilia; hemophilic athropathy; hyaluronic acid; chondroitin sulfate

Issue: 2017, Volume 68, Issue 5
Pages: 1028-1030
Publication date: 2017/6/15
https://doi.org/10.37358/RC.17.5.5604
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SIRBU, P.D., TUDOR, R., BADULESCU, O.V., Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients, Rev. Chim., 68(5), 2017, 1028-1030.

Vancouver
Sirbu PD, Tudor R, Badulescu OV. Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients. Rev. Chim.[internet]. 2017 May;68(5):1028-1030. Available from: https://doi.org/10.37358/RC.17.5.5604


APA 6th edition
Sirbu, P.D., Tudor, R. & Badulescu, O.V. (2017). Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients. Revista de Chimie, 68(5), 1028-1030. https://doi.org/10.37358/RC.17.5.5604


Harvard
Sirbu, P.D., Tudor, R., Badulescu, O.V. (2017). 'Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients', Revista de Chimie, 68(5), pp. 1028-1030. https://doi.org/10.37358/RC.17.5.5604


IEEE
P.D. Sirbu, R. Tudor, O.V. Badulescu, "Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients". Revista de Chimie, vol. 68, no. 5, pp. 1028-1030, 2017. [online]. https://doi.org/10.37358/RC.17.5.5604


Text
Paul Dan Sirbu, Razvan Tudor, Oana Viola Badulescu,
Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients,
Revista de Chimie,
Volume 68, Issue 5,
2017,
Pages 1028-1030,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.5.5604.
(https://revistadechimie.ro/Articles.asp?ID=5604)
Keywords: hemophilia; hemophilic athropathy; hyaluronic acid; chondroitin sulfate


RIS
TY - JOUR
T1 - Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients
A1 - Sirbu, Paul Dan
A2 - Tudor, Razvan
A3 - Badulescu, Oana Viola
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 5
SP - 1028
EP - 1030
UR - https://doi.org/10.37358/RC.17.5.5604
KW - hemophilia
KW - hemophilic athropathy
KW - hyaluronic acid
KW - chondroitin sulfate
ER -


BibTex
@article{RevCh2017P1028,
author = {Sirbu Paul Dan and Tudor Razvan and Badulescu Oana Viola},
title = {Hyaluronic Acid and Chondroitin Sulfate Viscosupplementation in Severe Arthropathy of Hemophilic Patients},
journal = {Revista de Chimie},
volume = {68},
number = {5},
pages = {1028-1030},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.5.5604},
url = {https://revistadechimie.ro/Articles.asp?ID=5604}
}
 
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