Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain

Popovici, Ramona Amina; Todor, Liana; Balean, Octavia; Motoc, Ovidiu; Podariu, Angela Codruta

Ramona Amina Popovici, Liana Todor, Octavia Balean, Ovidiu Motoc, Angela Codruta Podariu

Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain

Abstract:

Products frequently used in dental practice most often come into contact with tissues and cells and frequently produce their injury. The aim of the present study was to assess the effects of different products of dental use on cutaneous physiological parameters after topical application to hairless and colored mice. In order to conduct the present study, we used as materials the following solutions: Chlorhexidine digluconate 2%, Chlumsky and Walkhoff solutions and, also, SKH 1 and C57BL/6J mice. The mice were divided in 4 groups: control - no interventions, group 1 - Chlorhexidine solution was applied on the dorsal side of the mice, group 2 - mice were treated with Chlumsky solution and group 3 - mice that received Walkhoff. The treatment was applied daily for 5 days and skin parameters (melanin, erythema and hydration) were measured by the means of non-invasive techniques (mexametry and corneometry). After sacrification, samples of skin and internal organs were histopathological analyzed. Our data showed that topical administration of the three solutions was associated with changes in skin parameters values, such as: an increased erythema value and a decreased hydration status in all three groups as compared to control, but especially in the group of mice that received Walkhoff solution, results that were independent of mice strain. The toxicity of these solutions was confirmed by histological analysis.

Keywords:
chlorhexidine; Chlumsky; Walkhoff; skin parameters

Issue: 2017, Volume 68, Issue 2

Pages: 424-426

Publication date: 2017/3/15

https://doi.org/10.37358/RC.17.2.5468

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
POPOVICI, R.A., TODOR, L., BALEAN, O., MOTOC, O., PODARIU, A.C., Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain, Rev. Chim., 68(2), 2017, 424-426.

Vancouver
Popovici RA, Todor L, Balean O, Motoc O, Podariu AC. Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain. Rev. Chim.[internet]. 2017 Feb;68(2):424-426. Available from: https://doi.org/10.37358/RC.17.2.5468

APA 6th edition
Popovici, R.A., Todor, L., Balean, O., Motoc, O. & Podariu, A.C. (2017). Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain. Revista de Chimie, 68(2), 424-426. https://doi.org/10.37358/RC.17.2.5468

Harvard
Popovici, R.A., Todor, L., Balean, O., Motoc, O., Podariu, A.C. (2017). 'Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain', Revista de Chimie, 68(2), pp. 424-426. https://doi.org/10.37358/RC.17.2.5468

IEEE
R.A. Popovici, L. Todor, O. Balean, O. Motoc, A.C. Podariu, "Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain". Revista de Chimie, vol. 68, no. 2, pp. 424-426, 2017. [online]. https://doi.org/10.37358/RC.17.2.5468

Text
Ramona Amina Popovici, Liana Todor, Octavia Balean, Ovidiu Motoc, Angela Codruta Podariu,
Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain,
Revista de Chimie,
Volume 68, Issue 2,
2017,
Pages 424-426,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.2.5468.
(https://revistadechimie.ro/Articles.asp?ID=5468)
Keywords: chlorhexidine; Chlumsky; Walkhoff; skin parameters

RIS
TY - JOUR
T1 - Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain
A1 - Popovici, Ramona Amina
A2 - Todor, Liana
A3 - Balean, Octavia
A4 - Motoc, Ovidiu
A5 - Podariu, Angela Codruta
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 2
SP - 424
EP - 426
UR - https://doi.org/10.37358/RC.17.2.5468
KW - chlorhexidine
KW - Chlumsky
KW - Walkhoff
KW - skin parameters
ER -

BibTex
@article{RevCh2017P424,
author = {Popovici Ramona Amina and Todor Liana and Balean Octavia and Motoc Ovidiu and Podariu Angela Codruta},
title = {Assessment of the Effects of Several Products of Dental Use After Topical Administration to Different Mice Strain},
journal = {Revista de Chimie},
volume = {68},
number = {2},
pages = {424-426},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.2.5468},
url = {https://revistadechimie.ro/Articles.asp?ID=5468}
}

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