Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers

Ardelean, Florina; Vlase, Laurian; Mocan, Andrei Marius; Gheldiu, Ana Maria; Antal, Diana Simona; Trandafirescu, Cristina; Marginean, Otilia; Dragan, Simona

Florina Ardelean, Laurian Vlase, Andrei Marius Mocan, Ana Maria Gheldiu, Diana Simona Antal, Cristina Trandafirescu, Otilia Marginean, Simona Dragan

Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers

Abstract:

Dietary supplements containing natural compounds, including resveratrol, are increasingly used as health improving products. The present study had three objectives, namely: the quantification of resveratrol by HPLC-MS in nine dietary supplements, the qualitative and quantitative assessment of 18 phenolic acids and flavonoids in the same supplements, and finally the measurement of the antioxidant capacity of these products. The content of resveratrol in commercial samples ranged between 22.8 and 104.7 % of the declared amount. The highest number of polyphenols that could be quantified in a dietary supplement was nine. The values obtained for antioxidant capacity suggest that resveratrol supplements containing below 10 mg of the stilbene have, even in the presence of other components, a very low antioxidant capacity which may be insufficient for an attainment of the desired antioxidant status. To our knowledge, this is the first HPLC-analysis cumulating the quantification of resveratrol with that of eighteen other polyphenols in dietary supplements, giving an in-depth overview of their composition and health benefits from the viewpoint of antioxidant capacity.

Keywords:
resveratrol; antioxidant capacity; HPLC-MS; dietary supplements

Issue: 2017, Volume 68, Issue 2

Pages: 401-407

Publication date: 2017/3/15

https://doi.org/10.37358/RC.17.2.5463

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
ARDELEAN, F., VLASE, L., MOCAN, A.M., GHELDIU, A.M., ANTAL, D.S., TRANDAFIRESCU, C., MARGINEAN, O., DRAGAN, S., Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers, Rev. Chim., 68(2), 2017, 401-407.

Vancouver
Ardelean F, Vlase L, Mocan AM, Gheldiu AM, Antal DS, Trandafirescu C, Marginean O, Dragan S. Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers. Rev. Chim.[internet]. 2017 Feb;68(2):401-407. Available from: https://doi.org/10.37358/RC.17.2.5463

APA 6th edition
Ardelean, F., Vlase, L., Mocan, A.M., Gheldiu, A.M., Antal, D.S., Trandafirescu, C., Marginean, O. & Dragan, S. (2017). Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers. Revista de Chimie, 68(2), 401-407. https://doi.org/10.37358/RC.17.2.5463

Harvard
Ardelean, F., Vlase, L., Mocan, A.M., Gheldiu, A.M., Antal, D.S., Trandafirescu, C., Marginean, O., Dragan, S. (2017). 'Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers', Revista de Chimie, 68(2), pp. 401-407. https://doi.org/10.37358/RC.17.2.5463

IEEE
F. Ardelean, L. Vlase, A.M. Mocan, A.M. Gheldiu, D.S. Antal, C. Trandafirescu, O. Marginean, S. Dragan, "Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers". Revista de Chimie, vol. 68, no. 2, pp. 401-407, 2017. [online]. https://doi.org/10.37358/RC.17.2.5463

Text
Florina Ardelean, Laurian Vlase, Andrei Marius Mocan, Ana Maria Gheldiu, Diana Simona Antal, Cristina Trandafirescu, Otilia Marginean, Simona Dragan,
Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers,
Revista de Chimie,
Volume 68, Issue 2,
2017,
Pages 401-407,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.2.5463.
(https://revistadechimie.ro/Articles.asp?ID=5463)
Keywords: resveratrol; antioxidant capacity; HPLC-MS; dietary supplements

RIS
TY - JOUR
T1 - Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers
A1 - Ardelean, Florina
A2 - Vlase, Laurian
A3 - Mocan, Andrei Marius
A4 - Gheldiu, Ana Maria
A5 - Antal, Diana Simona
A6 - Trandafirescu, Cristina
A7 - Marginean, Otilia
A8 - Dragan, Simona
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 2
SP - 401
EP - 407
UR - https://doi.org/10.37358/RC.17.2.5463
KW - resveratrol
KW - antioxidant capacity
KW - HPLC-MS
KW - dietary supplements
ER -

BibTex
@article{RevCh2017P401,
author = {Ardelean Florina and Vlase Laurian and Mocan Andrei Marius and Gheldiu Ana Maria and Antal Diana Simona and Trandafirescu Cristina and Marginean Otilia and Dragan Simona},
title = {Dietary Supplements with Resveratrol, Flavonoids and Phenolic Acids: in-depth HPLC Profiling and Antioxidant Capacity as Quality Markers},
journal = {Revista de Chimie},
volume = {68},
number = {2},
pages = {401-407},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.2.5463},
url = {https://revistadechimie.ro/Articles.asp?ID=5463}
}

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