Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation

Giuroiu, Cristian Levente; Vataman, Maria; Melian, Gabriel; Bularda, Dragos; Lozneanu, Ludmila; Salceanu, Mihaela; Patrascu, Alexandru; Andrian, Sorin; Melian, Anca

Cristian Levente Giuroiu, Maria Vataman, Gabriel Melian, Dragos Bularda, Ludmila Lozneanu, Mihaela Salceanu, Alexandru Patrascu, Sorin Andrian, Anca Melian

Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation

Abstract:

The study aimed to assess the number, localization and distribution of interleukin 6 (IL-6) positive cells in healthy pulp, acute and chronic pulpitis. The study group included 48 patients aged between 18-72, treated in University of Medicine and Pharmacy Grigore T. Popa Iasi, Romania. The pulpectomy was performed on 42 patients diagnosed with acute and chronic pulpitis. The other 6 patients, without signs of dental caries or periodontal disease, were submitted to extractions of teeth for orthodontic purposes, with pulpectomy performed before extraction. The pulp samples were examined with optic microscope. The detection and assessment of IL-6 were performed using immunohistochemical technique. Data were statistically analysed using non-parametric tests. According to morphopathological criteria, 42.85% were classified as acute pulpitis and 57.14% as chronic pulpitis. The pulp samples in control group were not associated with IL-6 positive cells. The analysis of all samples with acute and chronic pulpitis identified 73.80% samples with IL-6 and 26.20% associated with the absence of IL-6. The highest frequency of IL-6 positive cells was recorded in rich-cell zone of crown dental pulp. The systemic distribution of IL-6 positive cells was mostly diffused without well-defined orientation. IL-6 release in acute and chronic pulpitis is significantly higher comparing with healthy pulp tissue.

Keywords:
acute pulpitis; chronic pulpitis; cytokine; ekoscope

Issue: 2017, Volume 68, Issue 2

Pages: 323-327

Publication date: 2017/3/15

https://doi.org/10.37358/RC.17.2.5445

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
GIUROIU, C.L., VATAMAN, M., MELIAN, G., BULARDA, D., LOZNEANU, L., SALCEANU, M., PATRASCU, A., ANDRIAN, S., MELIAN, A., Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation, Rev. Chim., 68(2), 2017, 323-327.

Vancouver
Giuroiu CL, Vataman M, Melian G, Bularda D, Lozneanu L, Salceanu M, Patrascu A, Andrian S, Melian A. Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation. Rev. Chim.[internet]. 2017 Feb;68(2):323-327. Available from: https://doi.org/10.37358/RC.17.2.5445

APA 6th edition
Giuroiu, C.L., Vataman, M., Melian, G., Bularda, D., Lozneanu, L., Salceanu, M.,... Melian, A. (2017). Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation. Revista de Chimie, 68(2), 323-327. https://doi.org/10.37358/RC.17.2.5445

Harvard
Giuroiu, C.L., Vataman, M., Melian, G., Bularda, D., Lozneanu, L., Salceanu, M., Patrascu, A., Andrian, S., Melian, A. (2017). 'Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation', Revista de Chimie, 68(2), pp. 323-327. https://doi.org/10.37358/RC.17.2.5445

IEEE
C.L. Giuroiu, M. Vataman, G. Melian, D. Bularda, L. Lozneanu, M. Salceanu, A. Patrascu, S. Andrian, A. Melian, "Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation". Revista de Chimie, vol. 68, no. 2, pp. 323-327, 2017. [online]. https://doi.org/10.37358/RC.17.2.5445

Text
Cristian Levente Giuroiu, Maria Vataman, Gabriel Melian, Dragos Bularda, Ludmila Lozneanu, Mihaela Salceanu, Alexandru Patrascu, Sorin Andrian, Anca Melian,
Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation,
Revista de Chimie,
Volume 68, Issue 2,
2017,
Pages 323-327,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.2.5445.
(https://revistadechimie.ro/Articles.asp?ID=5445)
Keywords: acute pulpitis; chronic pulpitis; cytokine; ekoscope

RIS
TY - JOUR
T1 - Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation
A1 - Giuroiu, Cristian Levente
A2 - Vataman, Maria
A3 - Melian, Gabriel
A4 - Bularda, Dragos
A5 - Lozneanu, Ludmila
A6 - Salceanu, Mihaela
A7 - Patrascu, Alexandru
A8 - Andrian, Sorin
A9 - Melian, Anca
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 2
SP - 323
EP - 327
UR - https://doi.org/10.37358/RC.17.2.5445
KW - acute pulpitis
KW - chronic pulpitis
KW - cytokine
KW - ekoscope
ER -

BibTex
@article{RevCh2017P323,
author = {Giuroiu Cristian Levente and Vataman Maria and Melian Gabriel and Bularda Dragos and Lozneanu Ludmila and Salceanu Mihaela and Patrascu Alexandru and Andrian Sorin and Melian Anca},
title = {Detection and Assessment of Interleukin 6 in Irreversible Pulp Inflamation},
journal = {Revista de Chimie},
volume = {68},
number = {2},
pages = {323-327},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.2.5445},
url = {https://revistadechimie.ro/Articles.asp?ID=5445}
}

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