Bisphosphonates in Bone Diseases Treatment

Lazar, Adela Cristina; Pacurar, Mariana; Campian, Radu Septimiu

Adela Cristina Lazar, Mariana Pacurar, Radu Septimiu Campian

Bisphosphonates in Bone Diseases Treatment

Abstract:

Bisphosphonates are the most frequently used drugs in the treatment of various bone and cancer diseases. They are complex chemical compounds, having a structure similar to that of pyrophosphates, but with certain differences: i.e., bisphosphonates have P-C-P in their composition; instead of an oxygen atom, a carbon atom is present. The R1 and R2 chains bind to the carbon atom and thus, the antiresorptive capacity of bisphosphonates on the one hand, and their bone-binding capacity on the other hand are stimulated. Through their action, they favor the treatment of diseases for which they have been prescribed, but they can also favor a number of undesired side effects.

Keywords:
bisphosphonates; nitrogen atoms; ATP; osteoporosis; treatment

Issue: 2017, Volume 68, Issue 2

Pages: 246-249

Publication date: 2017/3/15

https://doi.org/10.37358/RC.17.2.5429

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
LAZAR, A.C., PACURAR, M., CAMPIAN, R.S., Bisphosphonates in Bone Diseases Treatment, Rev. Chim., 68(2), 2017, 246-249.

Vancouver
Lazar AC, Pacurar M, Campian RS. Bisphosphonates in Bone Diseases Treatment. Rev. Chim.[internet]. 2017 Feb;68(2):246-249. Available from: https://doi.org/10.37358/RC.17.2.5429

APA 6th edition
Lazar, A.C., Pacurar, M. & Campian, R.S. (2017). Bisphosphonates in Bone Diseases Treatment. Revista de Chimie, 68(2), 246-249. https://doi.org/10.37358/RC.17.2.5429

Harvard
Lazar, A.C., Pacurar, M., Campian, R.S. (2017). 'Bisphosphonates in Bone Diseases Treatment', Revista de Chimie, 68(2), pp. 246-249. https://doi.org/10.37358/RC.17.2.5429

IEEE
A.C. Lazar, M. Pacurar, R.S. Campian, "Bisphosphonates in Bone Diseases Treatment". Revista de Chimie, vol. 68, no. 2, pp. 246-249, 2017. [online]. https://doi.org/10.37358/RC.17.2.5429

Text
Adela Cristina Lazar, Mariana Pacurar, Radu Septimiu Campian,
Bisphosphonates in Bone Diseases Treatment,
Revista de Chimie,
Volume 68, Issue 2,
2017,
Pages 246-249,
ISSN 2668-8212,
https://doi.org/10.37358/RC.17.2.5429.
(https://revistadechimie.ro/Articles.asp?ID=5429)
Keywords: bisphosphonates; nitrogen atoms; ATP; osteoporosis; treatment

RIS
TY - JOUR
T1 - Bisphosphonates in Bone Diseases Treatment
A1 - Lazar, Adela Cristina
A2 - Pacurar, Mariana
A3 - Campian, Radu Septimiu
JF - Revista de Chimie
JO - Rev. Chim.
PB - Revista de Chimie SRL
SN - 2668-8212
Y1 - 2017
VL - 68
IS - 2
SP - 246
EP - 249
UR - https://doi.org/10.37358/RC.17.2.5429
KW - bisphosphonates
KW - nitrogen atoms
KW - ATP
KW - osteoporosis
KW - treatment
ER -

BibTex
@article{RevCh2017P246,
author = {Lazar Adela Cristina and Pacurar Mariana and Campian Radu Septimiu},
title = {Bisphosphonates in Bone Diseases Treatment},
journal = {Revista de Chimie},
volume = {68},
number = {2},
pages = {246-249},
year = {2017},
issn = {2668-8212},
doi = {https://doi.org/10.37358/RC.17.2.5429},
url = {https://revistadechimie.ro/Articles.asp?ID=5429}
}

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